Hepatitis viruses and antiphospholipid autoantibodies

Hepatitis Viruses Seromarkers and Liver Function inGuilan Hemophiliacs

Abstract There are some reports about hepatitis B and C Virus infection in hemophiliacs in different part of our country. We studied Guilan Province hemophiliacs to determine the frequency of hepatitis B surface antigen (HbsAg), anti hepatitis C antibody and liver function test impairments. This study was done from Feb to Apr 1999 among hemophiliacs registered in Guilan Hemophilia Society. Pat...

Seroprevalence of Hepatitis A and Hepatitis B Viruses Among Blood Donors in North of Iran

Background and Objective: Hepatitis A virus (HAV) and hepatitis E virus (HEV) are both transmitted by the fecal-oral route and are known as leading causes of acute viral hepatitis in the world, especially in developing countries. There is a lack of updated data on HAV and HEV seroprevalence in the north of Iran. This study aimed to determine the seroprevalence of HAV and HEV among blood donors ...

Apoptotic antigens, B2-glycoprotein I, and antiphospholipid autoantibodies.

Autoantibodies to phospholipid-binding plasma proteins: a new view of lupus anticoagulants and other "antiphospholipid" autoantibodies.

L UPUS ANTICOAGULANTS, and “antiphospholipid” autoantibodies in general, are of considerable clinical importance because of their strong association with thrombosis, recurrent fetal loss, and thrombocytopenia, ie, the “antiphospholipid” antibody syndrome.’ This review focuses on recent evidence that “antiphospholipid” autoantibodies are not directed against anionic phospholipids, as has previou...

Autoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndrome.

The association of thrombosis and gestational morbidity with antiphospholipid antibodies is termed antiphospholipid syndrome (APS). Annexin 2 (A2) is a profibrinolytic endothelial cell surface receptor that binds plasminogen, its tissue activator (tPA), and beta(2)-glycoprotein I (beta2GPI), the main antigen for antiphospholipid antibodies. Here, we evaluate A2 as a target antigen in APS. Serum...